2)¨**********APA norms 4) **********References from the last 5 years 5) The questions don’t be must copied in the work. It must be identified by numbers. For example 1. The difference is………………………….. 2. The difference is………………………… 3.The possible mechanisms are………………………… ________________________________________________________ Case: Two professional registered nurses are interested in evidence-based practice and have developed research questions to study.  The nurses discuss what evidence-based practice is all about and are trying to determine if the organizational culture supports nurses who seek out and use research to change long-standing practices that are rooted in tradition rather than science. 1. What is the best explanation of the difference between evidence-based practice and best practices? 2. The two registered nurses review a variety of research studies to answer their proposed research questions. What is the difference in the efficacy of randomized controlled trials, integrative reviews, or meta-analysis with practice-based evidence for continuous process improvement? 3. The registered professional nurses must consider alternative support mechanisms when searching for the best evidence to support their clinical practice. What are possible mechanisms of support for evidence-based practice? 4.  Describe the challenges that exist today for nurses in implementing evidence-based practice?

Evidence-based practice (EBP) is an essential concept in healthcare that involves integrating the best available evidence with clinical expertise and patient preferences to make decisions about patient care. On the other hand, best practices refer to approaches or interventions that have consistently demonstrated superior outcomes in a specific context. While there is some overlap between the two concepts, there are distinct differences.

The main difference between evidence-based practice and best practices lies in the level of rigor involved in their development and implementation. EBP emphasizes the use of empirical evidence from well-designed research studies, such as randomized controlled trials (RCTs), to guide clinical decision-making. These studies typically involve comparison groups, randomization, and control of biases to establish causal relationships between interventions and outcomes. The evidence derived from RCTs is considered to be of high quality and is the gold standard for EBP.

On the other hand, best practices may not always be supported by strong empirical evidence. They may arise from expert opinion, professional consensus, or tradition. While best practices may be effective in certain contexts, their efficacy may not have been rigorously tested through research. These practices often emerge from experience or patterns of successful outcomes in specific clinical settings. Best practices can be a starting point for EBP but need to be critically evaluated within the context of the available evidence.

The two registered nurses in the case study are reviewing various types of research studies to answer their research questions. They should consider the differences in efficacy between RCTs, integrative reviews, or meta-analyses, and practice-based evidence for continuous process improvement.

RCTs are considered the gold standard for assessing the efficacy of interventions. They involve randomly assigning participants to different groups to compare the effects of an intervention against a control group or another intervention. RCTs provide a high level of evidence as they control for biases and confounding factors, allowing researchers to establish causal relationships between interventions and outcomes.

Integrative reviews and meta-analyses, on the other hand, are systematic reviews of existing research studies. Integrative reviews aim to synthesize a diverse range of research studies to provide a comprehensive overview of a particular topic. Meta-analyses, on the other hand, involve statistical techniques to pool data from multiple studies and quantitatively analyze the overall effect size of an intervention. These types of reviews provide a higher level of evidence than individual studies alone and can help inform clinical decision-making.

Practice-based evidence refers to evidence derived from the direct experience of practitioners in real-world clinical settings. While practice-based evidence can provide valuable insights into clinical practice, it is generally considered to be of lower methodological quality than research studies. However, it is important to consider the context and relevance of practice-based evidence in the absence of high-quality research.

The registered professional nurses in the case study need to explore alternative support mechanisms for evidence-based practice. There are several possible mechanisms that can facilitate the integration of research findings into clinical practice.

Firstly, access to scholarly databases and resources is crucial for nurses to locate and retrieve relevant research articles. Institutions should provide nurses with subscriptions to databases and journals to ensure they have access to the latest evidence. Additionally, organizations can establish digital libraries or knowledge repositories to store and share research articles, guidelines, and other relevant resources.

Secondly, ongoing education and training programs can enhance nurses’ skills in interpreting and applying research evidence. Workshops, seminars, and online courses can provide opportunities for nurses to develop critical appraisal skills, understand research methodologies, and learn how to incorporate evidence into their practice.

Thirdly, creating a culture that values and prioritizes EBP is essential to support nurses in their evidence-based practice journey. This involves establishing policies, guidelines, and protocols that encourage the use of research evidence, providing mentorship and support for nurses, and incorporating EBP into performance evaluations and professional development plans.

In conclusion, evidence-based practice involves integrating research evidence, clinical expertise, and patient preferences to guide decision-making in healthcare. While best practices can provide initial guidance, EBP emphasizes the use of rigorous research evidence, particularly from RCTs, to inform clinical practice. Nurses must consider the efficacy of different types of research studies, such as integrative reviews and meta-analyses, in comparison to practice-based evidence. Additionally, support mechanisms such as access to resources, education and training, and creating a supportive organizational culture are crucial for nurses to implement EBP successfully. The challenges that exist today for nurses in implementing EBP include limited access to research resources, lack of research literacy skills, resistance to change, and time constraints. Addressing these challenges requires a multi-faceted approach involving organizational support and ongoing education and training initiatives.