# 4-Interaction in statistics can be defined as the effect of one independent variable may depend on the level of the other independent variable. In statistics, an interaction may arise when considering the relationship among three or more variables, and describes a situation in which the simultaneous influence of two variables on the third is not additive. In order to find an interaction, you must have a factorial design, in which the two or more independent variables are “crossed” with one another so that there are observations at every combination of levels of the two independent variables. The presence of interaction can have important implications for the interpretation of statistical models. If two variables of interest interact, the relationship between each of the interacting variables and a third “dependent variable” depends on the value of the other interacting variables and this makes it hardest to anticipate or predict the consequences of the value of variable that changes particularly if the variable it interacts with are difficult to control. (Eastern & McColl 2016) Example is if we want to examine the effect of two variables, gender and premature birth on health outcomes, we would first of all outline any differences in health outcome score among gender as a main effect.  Similarly, we will describe any difference in the scores of full term/premature as a main effect.  The presence of an interaction effect shows that the effect of gender on health outcome varies as a function of premature birth status. Reference Easton J.C & McColl 2016: Design of Experiments and Anova.  Retrieved August 17, 2018 from . 5-Thank you all for sharing your examples of the variables interaction. Suppose you formulate a hypothesis and conduct an experiment, but the results were not significant. What information can you gain from that, or has your experiment been a failure? Support your argument with example. 6- for your example. The interaction effect here is useful as it is an indication for the treatment efficacy. It is important to consider different factors when assigning the treatment for the patient, for example looking at the effect at different age, by gender and if the patient will go with one treatment, diet or pills, or both.

Interaction in statistics refers to the effect of one independent variable depending on the level of another independent variable. It is a concept that arises when considering the relationship among three or more variables and describes a situation where the simultaneous influence of two variables on the third is not simply additive.

To identify an interaction, a factorial design is necessary. In this design, two or more independent variables are crossed with each other, resulting in observations at every combination of levels of the independent variables. This allows for the examination of how the variables interact with each other.

The presence of an interaction can have significant implications for the interpretation of statistical models. When two variables interact, the relationship between each of the interacting variables and a third variable, known as the dependent variable, depends on the value of the other interacting variable. This complicates the process of anticipating or predicting the consequences of changes in a particular variable, especially if the variable it interacts with is difficult to control.

To illustrate this concept, let’s consider a hypothetical study examining the effect of two variables, gender and premature birth, on health outcomes. We would first analyze any differences in health outcome scores between genders as a main effect. Similarly, we would analyze any differences in scores between full-term and premature births as a main effect. However, the presence of an interaction effect would indicate that the effect of gender on health outcomes varies depending on premature birth status. In other words, the relationship between gender and health outcomes is not the same for both full-term and premature births.

In this example, understanding the interaction effect is important for accurately interpreting the findings of the study. It highlights the need to consider additional factors, such as premature birth status, when examining the relationship between gender and health outcomes.

Now, let’s consider the scenario where an experiment is conducted and the results are not statistically significant. Does this mean that the experiment has been a failure? Not necessarily. The lack of statistical significance in a study can provide valuable information and should not be automatically considered a failure.

When the results of an experiment are not statistically significant, it may indicate that there is no evidence of a relationship or effect between the variables under investigation. This can be informative in itself, as it suggests that the hypothesized relationship or effect may not exist.

For example, suppose a researcher conducts a study to investigate the effect of a new medication on reducing pain. If the results of the study do not show a statistically significant difference in pain levels between the treatment group and the control group, it suggests that the medication may not have a significant effect on pain reduction.

However, it is important to note that the lack of statistical significance does not definitively prove the absence of a relationship or effect. It may simply indicate that the sample size was too small or that other factors influenced the results. In such cases, further research with a larger sample size or additional control measures may be necessary.

In conclusion, interaction in statistics refers to the effect of one independent variable depending on the level of another independent variable. It is important to consider and analyze interaction effects in statistical models as they can have implications for the interpretation of results. When the results of an experiment are not statistically significant, it can provide useful information about the absence of a relationship or effect, but it should not be automatically considered a failure. Additional research or modifications to the study design may be needed to further investigate the variables of interest.