An understanding of the factors surrounding women’s and men’s health, infections, and hematologic disorders can be critically important to disease diagnosis and treatment in these areas. This importance is magnified by the fact that some diseases and disorders manifest differently based on the sex of the patient.  Effective disease analysis often requires an understanding that goes beyond the human systems involved. The impact of patient characteristics, as well as racial and ethnic variables, can also have an important impact. An understanding of the symptoms of alterations in systems based on these characteristics is a critical step in diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans. In this Assignment, you examine a case study and analyze the symptoms presented. You identify the elements that may be factors in the diagnosis, and you explain the implications to patient health. Assignment (2-page case study analysis) In your Case Study Analysis related to the scenario provided, explain the following: · You may also want to briefly explain: · The factors that affect fertility (STDs). · Why inflammatory markers rise in STD/PID. · Why prostatitis and infection happens. Also explain the causes of systemic reaction. · Why a patient would need a splenectomy after a diagnosis of ITP. Case Study: 67-year-old female presents with chief complaint of shortness of breath, fatigue, weakness, unintentional weight loss, and mild numbness in her feet. She states she feels unsteady when she walks. PMH includes hypothyroidism well controlled on Synthroid 100 mcg/day. No hx of HTN or CHF. Vital signs: Temp 98.7 F, pulse 118, Respirations 22, BP 108/64, PaO2 95% on room air. Physical exam revealed pale, anxious female appearing older than stated years. HEENT- pale conjunctiva of eyes and pale palate. Tongue beefy red and slightly swollen with loss of normal rugae. Turbinates pale but no swelling. Thyroid palpable but no nodules felt. No lymph nodes palpated. Cardiac-regular rate and rhythm with soft II/VI systolic murmur. Respiratory- lungs clear with no adventitious breath sounds. Abdomen-soft, non-tender with positive bowel sounds. Liver edge palpated two finger breadths below right costal margin. Lab data- hgb, hct, reticulocyte count, serum B12 levels low, mean corpuscle volume, plasma iron, and ferritin levels high, folate, TIBC are normal. The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references.

Title: Case Study Analysis: Factors Affecting Women’s and Men’s Health, Infections, and Hematologic Disorders


In this case study analysis, we will explore the symptoms presented by a 67-year-old female patient and discuss the factors that may impact her diagnosis and overall health. It is crucial to understand the complexities of women’s and men’s health, infections, and hematologic disorders as they can manifest differently based on the patient’s sex and other variables such as race and ethnicity. This understanding is vital for disease diagnosis, treatment, patient education, and guiding treatment plans for Advanced Practice Registered Nurses (APRNs).

Case Study:

The 67-year-old female patient presents with several chief complaints, including shortness of breath, fatigue, weakness, unintentional weight loss, and mild numbness in her feet. She also reports feeling unsteady when walking. Her past medical history (PMH) includes well-controlled hypothyroidism on Synthroid 100 mcg/day, with no history of hypertension (HTN) or congestive heart failure (CHF).

Upon physical examination, the patient appears pale, anxious, and older than her stated age. Her conjunctiva of the eyes and palate are pale, while her tongue appears beefy red, slightly swollen, and lacking normal rugae. Turbinates show no swelling, and palpation of the thyroid reveals no nodules or abnormalities. There are no palpable lymph nodes. Cardiac examination reveals a regular rate and rhythm with a soft II/VI systolic murmur. Lungs are clear with no adventitious breath sounds, and the abdomen is soft, non-tender, with positive bowel sounds. The liver edge is palpated two finger breadths below the right costal margin.

Lab data reveals low levels of hemoglobin (hgb), hematocrit (hct), reticulocyte count, and serum B12. Mean corpuscle volume, plasma iron, and ferritin levels are elevated, while folate and total iron-binding capacity (TIBC) are within normal ranges.


The presented symptoms in this case study suggest several potential factors that could be influencing the diagnosis and subsequent treatment plan. These factors include fertility issues related to sexually transmitted diseases (STDs), inflammatory markers rising in STD/pelvic inflammatory disease (PID), the occurrence of prostatitis and infection, causes of systemic reaction, and the need for a splenectomy following a diagnosis of immune thrombocytopenic purpura (ITP).

Firstly, it is important to consider the impact of STDs on fertility. STDs, such as chlamydia and gonorrhea, can lead to pelvic inflammatory disease (PID) in women. PID can cause inflammation in the reproductive organs, leading to scarring and blockages. It can result in fertility issues, such as tubal blockages, ectopic pregnancies, and pelvic pain. Therefore, it is crucial to assess the patient’s history of STDs to determine if they are contributing to her symptoms.

Inflammatory markers, such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), rise in response to inflammation in the body. In the case of STD/PID, inflammation in the reproductive organs can lead to an increase in these markers. Elevated inflammatory markers serve as indicators of ongoing infection or inflammation, aiding in the diagnosis and monitoring of diseases. The rise in inflammatory markers in this patient could be attributed to the underlying infection or inflammation associated with STD or PID.

Prostatitis is inflammation of the prostate gland, commonly caused by a bacterial infection. Infection can occur due to ascending spread from the urinary tract or through direct inoculation during sexual activity. The symptoms reported by the patient, such as fatigue, weakness, and urinary symptoms, are consistent with prostatitis. Identifying the underlying cause of prostatitis is essential for appropriate treatment.

Systemic reaction refers to a cascade of immune responses that occur in the body in response to infection, inflammation, or other stimuli. It involves the release of inflammatory mediators and activation of immune cells. The causes of systemic reaction can range from severe infections like sepsis to autoimmune diseases. Evaluation of the patient’s medical history, symptoms, and lab data can help determine the underlying cause of the systemic reaction observed.

ITP is an autoimmune disorder characterized by low platelet counts due to increased destruction by the immune system. Splenectomy, the surgical removal of the spleen, is sometimes necessary for patients with ITP who do not respond to other treatments. The spleen plays a role in platelet destruction; hence its removal can help increase platelet counts. Understanding the need for a splenectomy in this patient following a diagnosis of ITP is crucial for managing her condition effectively.


In conclusion, analyzing this case study requires a multidimensional understanding of factors that impact women’s and men’s health, infections, and hematologic disorders. Considering the relationship between fertility and STDs, the rise of inflammatory markers in STD/PID, the causes of prostatitis and systemic reaction, and the necessity of a splenectomy after ITP diagnosis, allows for a comprehensive evaluation of the patient’s symptoms. This analysis aids in the accurate diagnosis, treatment, patient education, and formulation of an appropriate treatment plan for APRNs.