List three classes of drugs affecting the Hematopoietic System
Drugs affecting the Hematopoietic system are commonly used as chemotherapy medications and may also be used for other reasons such as treating certain types of anemia or bone marrow suppression. The specific class of drug a doctor prescribes will be based on what the patient is being treated for and in what stage it is.
Three classes of drugs that have an effect on the hematopoietic system are radiation, chemotherapeutic agents, and anti-metabolites. Drugs in this class work by interfering with the normal processes that would otherwise keep cells from reproducing, known as cellular mitosis. This class of drugs has little to no effect on normal cells, but can be very toxic to cancer cells. These medications are usually given via IV once every several days and should be monitored closely for signs of toxicity (immune suppression).
Hematopoietic System. The hemopoietic system which is also known as the hematopoiesis refers to the process in our body of creating blood cells. The functions of red blood cells, white blood cells and platelets are considered part of this system. There are three classes of drugs, the most common being chemotherapy or cytotoxic chemotherapy. This class works by interfering with cell division which prevents tumor growth and spread. The mechanism for this class is usually disrupting functions within the cell’s mitochondria or DNA. Chemotherapy is frequently used to treat cancer, tumors, leukemia and diseases such as multiple myeloma, Hodgkin’s lymphoma and Non-Hodgkin’s Lymphoma. It is triggered by a cause but can be done preventively as well. Medications that fall under this category include: Busulfan Carboplatin Doxorubicin Daunorubicin Epirubicin Estramustine Idarubicin Mechlorethamine Mitomycin C Vincristine Doxycycline Methotrexate
The hematopoietic system refers to the bone marrow, bone, and tissues that produce blood cells. The three main classes of drugs affecting the hematopoietic system are: red cell stabilizers, coagulation modifiers, and anti-cancer molecules.
The three classes of drugs used to treat disorders affecting the hematopoietic system include antineoplastics, control agents and blood modifiers.
Hematopoietic System: The hematopoietic system is responsible for formation of blood cells. They serve as the body’s main detoxifying organ. Disorders that affect this system are anemia, hemaglobinopathies, leukopenias, leukocytoses, etc. Medications include (but are not limited to) Antihistamines (counteract allergic reactions), antibiotic and antibacterial agents (used to treat infections), digestive agents (to treat digestive disorders), anticoagulant/antiplatelets agents (prevent clotting), chemotherapeutics (used to treat certain types of cancers) among others.
The hematopoietic system refers to the process of blood cell formation, and regular monitoring of the bone marrow is of extreme importance in the case of patients being treated with drugs that affect blood cell production, such as antibiotics for bacterial infections.
The hem·a·to·poi·e·tic sys·tem is a group of organs and tissues that produce red blood cells, white blood cells (WBCs), and platelets. Production of these cells occurs in the bone marrow, lymph nodes and spleen. Red blood cells pick up oxygen in the lungs and carry it through blood vessels to all organs, tissues and cells. WBCs perform important immune system functions such as fighting bacteria, viruses or other foreign invaders or products. Platelets are involved in blood clotting.
A drug that is used to treat tumors is chemotherapy. Chemotherapy is a treatment of cancer by the administration of drugs. These drugs are called cytotoxic agents, they kill fast-growing cells, They kill cancer cells and they also kill normal fast-growing tissue, including blood cells and intestinal cells.
List three classes of drugs affecting the Hematopoietic System. List the mechanism of action for each class of drug. Choose one medication from the three classes and discuss what disorder the drug is used to treat? How often the medication is given? What labs should get monitored while the patient is taking this medication? Your response should be at least 350 words.