No plagiarism will be accepted Instructions: Body of textHistory-history of creation/discovery and use-describe the chemical make-up of the drug (i.e., Crack is cocaine hydrochloride powder that has been processed to form a rock crystal that is then usually smoked). At least half a page. Production-is the drug natural or synthesized in the lab? Ex: designer drug LSD (lab) versus naturally growing mushrooms (natural).  At least half a page. Influence on Neurotransmitters and Receptors-Describe what neurotransmitters/receptors/hormones are involved. How does the drug influence them? (be specific, i.e., serotonin receptors or even more specific, 5HT). At least half a page. Effectiveness, Use and/or Abuse-what is the effectiveness of the drug (if it is used clinically) or if illicit, how potent is it (maybe talk here about cutting street drugs with other chemicals like baking soda, etc). -is the drug abused? If yes describe in terms of prevalence of use and abuse. If no describe why-is the drug addictive or does it build a physical tolerance (need to increase the dose to keep working)? If yes then how do you stop using it (taper down the dose, etc.). If no, then say why the receptors that it works on do not up or down regulate, etc.).  At least a page. Physical, Mental, and Social Benefits/Dangers -Is this drug dangerous or useful or beneficial (physical, to the self,  the repercussions to society, to research, and the field of psychology) describe how and why? At least a page.Conclusion -write a brief summary of the main points. -based on the research, is there conflicting data about the drug? Is this supported by research? Mention any discrepancies in the research that should be addressed. A research paper is required to pass the course.  A 6 page APA paper based on a related biological psychology topic/phenomenon. On this paper, you will explore the influence and effects of a specific drug e.g. caffeine, alcohol, cocaine, Ritalin, etc.  on a specific target population of interest e.g. young college students, children with ADHD, women with bipolar disorder, young women with anorexia, Number of Pages: 6 Pages Page Line Spacing: Double spaced (Default) Academic Level: College Paper Format: APA

Title: The Influence and Effects of Cocaine on Neurotransmitters and Receptors

1. Introduction
Cocaine is a highly potent stimulant drug that has gained notoriety for its powerful effects on the central nervous system. This research paper aims to explore the history, production, influence on neurotransmitters and receptors, effectiveness, use and abuse, as well as the physical, mental, and social benefits and dangers associated with cocaine. Through a comprehensive analysis, this paper will provide valuable insights into the pharmacological aspects of cocaine and its impact on individuals and society.

2. History and Production
Cocaine was first isolated from the coca plant in the mid-19th century by German chemist Albert Niemann. Initially used for its local anesthetic properties, cocaine was later recognized for its stimulant effects. Today, cocaine is illicitly manufactured from the leaves of the coca plant, primarily grown in South America. The extraction process involves refining the leaves to obtain the cocaine alkaloid, which is then further processed into different forms, including cocaine hydrochloride powder (commonly known as “powder cocaine”) and crack cocaine. While powder cocaine is predominantly snorted or dissolved for intravenous use, crack cocaine is typically smoked. This variation in administration routes affects the intensity and duration of its effects.

3. Chemical Makeup
Cocaine hydrochloride powder, the most common form of cocaine, is chemically composed of a compound known as benzoylmethylecgonine. It acts by inhibiting the reuptake of key neurotransmitters, such as dopamine, serotonin, and norepinephrine, leading to their accumulation at postsynaptic receptors and producing the characteristic stimulant effects. The molecular structure of cocaine allows it to readily cross the blood-brain barrier, resulting in rapid onset and intense psychoactive effects.

4. Influence on Neurotransmitters and Receptors
Cocaine exerts its effects primarily through its interaction with dopamine transporters, blocking dopamine reuptake and increasing its availability in the synaptic cleft. The elevated dopamine levels contribute to the euphoria and heightened arousal commonly experienced by cocaine users. Additionally, cocaine also affects other neurotransmitters such as serotonin and norepinephrine, albeit to a lesser extent. These interactions result in a complex interplay of neurochemical responses, leading to the various psychological and physiological effects associated with cocaine use.

5. Effectiveness, Use, and Abuse
In clinical settings, cocaine is rarely used due to its high abuse potential and detrimental effects. However, illicitly, it is abused for its intense euphoric effects. The potency of cocaine varies depending on factors such as purity, administration route, and individual susceptibility. Street drugs are often adulterated or “cut” with other substances, such as baking soda or talcum powder, to increase profits. This adulteration can lead to unpredictable and potentially dangerous effects on users.

Cocaine is highly addictive, primarily due to its impact on the reward pathways in the brain. Chronic use of cocaine can result in the development of physical dependence and tolerance, requiring higher doses to achieve the desired effects. Discontinuing cocaine use can be challenging and may lead to withdrawal symptoms, including depression, fatigue, and cravings. Tapering down the dose and seeking support from healthcare professionals are common strategies to facilitate cocaine cessation.

6. Physical, Mental, and Social Benefits/Dangers
While cocaine may initially produce feelings of euphoria and increased energy, its long-term use is associated with severe physical, mental, and social dangers. Physically, cocaine abuse can lead to cardiovascular complications, such as hypertension, heart attacks, and strokes. Additionally, it can cause respiratory problems, nasal damage, and gastrointestinal issues. Mentally, chronic cocaine use can result in cognitive impairments, including attention deficits and memory loss. Socially, cocaine addiction often leads to strained relationships, financial problems, legal issues, and an increased risk of engaging in risky behaviors.

7. Conclusion
In conclusion, cocaine is a powerful stimulant drug that exerts its effects through its interaction with neurotransmitters and receptors in the brain. Its history, production methods, and administration routes all contribute to variations in its potency and effects on individuals. Despite its initial pleasurable effects, long-term cocaine use can lead to addiction and have detrimental effects on physical, mental, and social well-being. It is crucial to raise awareness about the risks associated with cocaine use and provide support for individuals struggling with addiction. Further research is needed to address discrepancies in understanding the complex pharmacological and psychological mechanisms underlying cocaine addiction.