NUR 1172 Most oral medications are subject to the first-pass mechanism

NUR 1172 Most oral medications are subject to the first-pass mechanism. Which food interferes with this mechanism resulting in increased serum drug levels?

Answer:

The first-pass mechanism is a process in which the liver metabolizes drugs taken orally.

The first-pass mechanism occurs when drugs are absorbed through the intestinal wall and go to the liver before entering the blood stream. The liver metabolizes these drugs, and the metabolites enter the body’s general circulation.

This means that some medications don’t reach their intended destination in sufficient quantities because most oral medications are subject to this mechanism.

The food that interferes with this mechanism resulting in increased serum drug levels is grapefruit juice.

Question:

NUR 1172 Most oral medications are subject to the first-pass mechanism. Which food interferes with this mechanism resulting in increased serum drug levels?

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