Topic: Chronic stable angina Type of paper: Research paper Discipline: Health Care and Life Sciences : Nursing Format or citation style: APA Chronic Stable Angina E.H. is a 45-year-old African American man who recently moved to the community from another state. He requests renewal of a prescription for a calcium channel blocker, prescribed by a physician in the former state. He is unemployed and lives with a woman, their son, and the woman’s 2 children. His past medical history is remarkable for asthma and six “heart attacks” that he claims occurred because of a 25-year history of drug use (primarily cocaine). He states that he used drugs as recently as 2 weeks ago. He does not have any prior medical records with him. He claims that he has been having occasional periods of chest pain. He is unable to report the duration or pattern of the pain. Before proceeding, explore the following questions: What further information would you need to diagnose angina (substantiate your answer)? What is the connection between cocaine use and angina? Identify at least three tests that you would order to diagnose angina. Diagnosis: Angina 1. List specific goals of treatment for E.H. 2. What dietary and lifestyle changes should be recommended for this patient? 3. What drug therapy would you prescribe for E.H. and why? 4. How would you monitor for success in E.H.? 5. Describe one or two drug–drug or drug–food interactions for the selected agent. 6. List one or two adverse reactions for the selected agent that would cause you to change therapy. 7. What would be the choice for the second-line therapy? 8. Discuss specific patient education based on the prescribed first-line therapy. 9. What over-the-counter and/or alternative medications would be appropriate for E.H.? Thanks! Use APA 6th Edition Format and support your work with at least 3 peer-reviewed references within 5 years of publication. Remember that you need a cover page and a reference page. All paragraphs need to be cited properly. Please use headers.  All responses must be in a narrative format and each paragraph must have at least 4 sentences. Lastly, you must have at least 2 pages of content, no greater than 4 pages, excluding cover page and reference page.

Chronic stable angina is a common symptom of underlying coronary artery disease (CAD). It is characterized by recurrent episodes of chest pain or discomfort that typically occur with exertion or emotional stress and are relieved with rest or nitroglycerin. In order to diagnose angina, further information is needed to corroborate the patient’s presenting symptoms. This may include obtaining a detailed history of the chest pain, including the quality, location, duration, and precipitating factors. It is also important to assess for associated symptoms such as shortness of breath, diaphoresis, and radiation of pain to the jaw or left arm. Furthermore, a physical examination should be conducted to evaluate for possible signs of CAD such as hypertension, elevated cholesterol levels, and carotid bruits.

The connection between cocaine use and angina is well-documented. Cocaine is a potent vasoconstrictor that can lead to coronary artery spasm and myocardial ischemia. It increases the demand for oxygen by the heart and decreases the supply by narrowing the coronary arteries. Chronic cocaine use can also accelerate the progression of atherosclerosis and increase the risk of myocardial infarction. Therefore, it is crucial to assess the patient’s drug use history and educate him about the adverse effects of cocaine on cardiovascular health.

To diagnose angina, several tests are commonly ordered. The first-line test is an exercise stress test, which involves monitoring the patient’s electrocardiogram (ECG) while they walk on a treadmill or ride a stationary bike. This test can help identify exercise-induced changes in the ECG suggestive of ischemia. If the stress test is inconclusive or contraindicated, other diagnostic modalities can be considered. These may include imaging studies such as myocardial perfusion imaging or stress echocardiography, which can assess regional myocardial blood flow and function. Invasive coronary angiography may also be performed to directly visualize any obstructive lesions in the coronary arteries.

The goals of treatment for E.H. would be to relieve his anginal symptoms, improve his quality of life, and reduce the risk of cardiovascular events. This can be achieved through a combination of lifestyle modifications, pharmacotherapy, and if necessary, invasive procedures such as percutaneous coronary intervention or coronary artery bypass graft surgery. Dietary changes that should be recommended for E.H. include adopting a heart-healthy diet that is low in saturated and trans fats, cholesterol, and sodium. This would involve incorporating more fruits, vegetables, whole grains, and lean protein sources into his meals. Furthermore, he should be advised to limit his intake of alcohol and avoid smoking or exposure to secondhand smoke.

In terms of drug therapy, E.H. would likely benefit from the initiation of antianginal medications. The first-line agent of choice for chronic stable angina is a beta-blocker, such as metoprolol or atenolol. These medications can reduce myocardial oxygen demand by decreasing heart rate, blood pressure, and contractility. They can also improve exercise tolerance and reduce the frequency and severity of anginal episodes. Additionally, beta-blockers have been shown to improve long-term outcomes in patients with CAD. Careful monitoring of blood pressure and heart rate should be performed to ensure optimal dosing and titration of the medication.

One potential drug-drug interaction with beta-blockers is the concurrent use of calcium channel blockers. These medications can potentiate the effects of beta-blockers and may cause excessive bradycardia or hypotension. Therefore, caution should be exercised when prescribing these medications together and close monitoring for adverse effects is warranted. Another potential interaction involves the use of erectile dysfunction medications such as sildenafil (Viagra) or tadalafil (Cialis). These medications can also cause a drop in blood pressure and should be avoided in patients taking nitroglycerin or other nitrates for angina.

Adverse reactions to beta-blockers are generally well-tolerated but can include fatigue, dizziness, and sexual dysfunction. If any of these adverse reactions occur and significantly impact the patient’s quality of life, a change in therapy may be necessary. In such cases, a second-line therapy for angina may be considered. This could include the use of a calcium channel blocker, such as amlodipine or diltiazem. These medications can dilate coronary arteries and improve myocardial blood flow, thereby relieving anginal symptoms.

Patient education based on the prescribed first-line therapy should focus on the importance of medication adherence and the need for regular follow-up with healthcare providers. E.H. should be educated about the potential benefits and possible side effects of beta-blockers, as well as the need for close monitoring of blood pressure and heart rate. Additionally, he should be counseled on lifestyle modifications and encouraged to make healthy choices such as engaging in regular exercise and maintaining a balanced diet.

In terms of over-the-counter and alternative medications, E.H. should be cautious about using nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen for pain relief. These medications have been associated with an increased risk of adverse cardiovascular events, especially in patients with underlying CAD. Instead, acetaminophen can be recommended as a safer alternative. Additionally, herbal supplements such as ginseng, gingko biloba, or garlic can potentially interact with prescribed medications and should be used with caution. Any over-the-counter or alternative medications should be discussed with a healthcare provider before initiating therapy.

In conclusion, chronic stable angina is a common manifestation of underlying CAD. Proper diagnosis involves obtaining a detailed history and performing appropriate diagnostic tests. The treatment goals for patients with angina include symptom relief, improvement in quality of life, and reduction in cardiovascular risk. This is achieved through lifestyle modifications and pharmacotherapy, with beta-blockers being the first-line agent of choice. Patient education and careful monitoring are essential for successful management of chronic stable angina.